http://www.pathologyoutlines.com
Normal Plasma Cells:
- evolve from B lymphocyte
- medium-sized cell
- have an eccentric nucleus
- have well-defined Golgi apparatus
- cytoplasm has distinct sea blue/cornflower color
- chromatin organized in a pinwheel structure
Immunoglobulins:
- 5 types of immunoglobulins –
- IgG
- IgM
- IgD
- IgE
- IgA
- each immunoglobulin has –
- 4 polypeptide chains
- 2 H chains (heavy chains)
- gamma (γ)
- alpha (α)
- mu (µ)
- epsilon (ε)
- delta (δ)
- 2 L chains (light chains)
- kappa (κ)
- lambda (λ)
- immunoglobulins are assessed qualitatively and quantitatively
- immunoelectrophoresis separates immunoglobulins by using antibodies directed against each fraction and run through a gel medium with an electric field
reticulousness 